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CURRENT RESEARCH STUDIES

Mild Cognitive Impairment

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COGNIKET-MCI is a placebo-controlled trial investigating whether ketones and B vitamins help cognitive function for people with Mild Cognitive Impairment.

Mild Cognitive Impairment & Alzheimer's disease

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CLARITY-AD is a placebo-controlled trial in the Open Label Extension Phase, investigating whether drug, Lecanemab, helps slow the progression of Alzheimer’s disease.

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EVOKE and EVOKE Plus are placebo-controlled trials investigating whether drug, Semaglutide, may help with cognition and daily functioning. Semaglutide is already licensed to treat Type 2 Diabetes. 

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PEBBAL2 is an observational study investigating how the leakiness of the blood brain barrier and inflammation might contribute to cognitive decline in Alzheimer's disease.

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POLARIS-AD is a placebo-controlled trial investigating whether drug, AR1001, may help the blood vessels in the brain work better for people with Alzheimer's disease.

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TRAILBLAZER5 is a placebo-controlled trial investigating whether drug, Donanemab, may help slow the progression of Alzheimer’s disease.

Dementia with Lewy bodies
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COBALT is a placebo-controlled trial investigating whether Memantine improves health and functioning for people with Dementia with Lewy bodies. Memantine is already licensed to help treat symptoms in Alzheimer's disease. 

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BRIC is an observational study investigating how inflammation might play a role in cognitive problems for people with Lewy body dementia.

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REWIND-LB is a placebo-controlled trial investigating whether, Neflamapimod, may help learning, memory and cognitive function for people living with Lewy body dementia. 

Carers
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IACT4CARERS is an internet-based trial investigating whether Acceptance and Commitment Therapy improves the psychological wellbeing of carers supporting people living with dementia.

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