top of page

Research trials

For people living with Mild Cognitive Impairment

A person jumping above the sunset

COGNIKET-MCI is a placebo-controlled trial investigating whether ketones and B vitamins help cognitive function for people with Mild Cognitive Impairment.

For people with Mild Cognitive Impairment or Alzheimer's Disease

Two ladies taking part in an movement exercise

CLARITY-AD is a placebo-controlled trial in the Open Label Extension Phase, investigating whether drug, Lecanemab, helps slow the progression of Alzheimer’s disease.

Photograph of a clinician across the table from an older couple who are having a group discussion

EVOKE and EVOKE Plus are placebo-controlled trials investigating whether drug, Semaglutide, may help with cognition and daily functioning. Semaglutide is already licensed to treat Type 2 Diabetes. 

Illustration of a brain and brain blood vessels

PEBBAL2 is an observational study investigating how the leakiness of the blood brain barrier and inflammation might contribute to cognitive decline in Alzheimer's disease.

Image of blood cells

POLARIS-AD is a placebo-controlled trial investigating whether drug, AR1001, may help the blood vessels in the brain work better for people with Alzheimer's disease.

Photograph of a couple over 65 years of age smiling

TRAILBLAZER5 is a placebo-controlled trial investigating whether drug, Donanemab, may help slow the progression of Alzheimer’s disease.

For people living with dementia with Lewy Bodies
Two men outside smiling

COBALT is a placebo-controlled trial investigating whether Memantine improves health and functioning for people with dementia with Lewy bodies. Memantine is already licensed to help treat symptoms in Alzheimer's disease. 

Illustration of a brain with one area activated and glowing

BRIC is an observational study investigating how inflammation might play a role in cognitive problems for people with Lewy body dementia.

Healthy volunteers aged 65-80
Two ladies smiling

TrailRunner is a placebo-controlled trial evaluating whether Remternetug is safe, tolerable, and effective at slowing the onset of Alzheimer’s disease in people who are at risk. 

Memory Assessment & Research Centre Logo

Contact

Connect

  • Instagram
  • Facebook
  • Twitter
  • LinkedIn

Moorgreen Hospital
Botley Road, 
West End

Southampton, S030 3JB

United Kingdom

© 2025 by Memory Assessment & Research Centre. All right reserved.

Not to be reproduced in whole or in part without the permission of the copyright owner. 

bottom of page